Hi Raja, I think this is more like a question for your datacenter (private vs cloud) network performance. Whenever comes to the cross region/geo location replications, the performance usually depends on the following factors:
1. The size of the objects to replicate
2. The number of objects
3. The network connection speed between two regions.
Any of the above factor could impact your replication performance. Usually for multi-region configurations, the application code has to be region-aware and take care of heavy lifting with the correct region.
In Ceph context, in stead of having a single site cluster with cross region nodes, you might want to implement a multi-site ceph cluster instead. I will do another article about ceph multi-site design, will keep you posted! :)